Tantum Verde: instructions for using the spray and what it is needed for, price, reviews, analogues. Tantum Verde tablets: instructions for use and analogues of Tantum Verde, what treats

Tantum Verde is produced by the Italian company A.C.R.A.F. in various versions - in the form of a solution, tablets and spray. For the treatment of inflammation of the mucous membrane of the respiratory tract, it is optimal to use the latter.

Consumers give good reviews of the drug, noting its effectiveness and the relative rarity of side effects. What does Tantum Verde help with, and how to use it correctly in accordance with the instructions?

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Composition and form of spray Tantum Verde

Aerosol release form: 30 ml plastic bottles. The spray nozzle is equipped with a folding tube, with which it is convenient to spray the drug on the back wall of the throat, on the tonsils.

The active substance is a non-steroidal anti-inflammatory drug - benzydamine.

Additionally, Tantum Verde includes:

medical alcohol;
glycerol;
soda;
water.

Auxiliary components include flavoring additives, aromatizers, and preservatives.

Instructions for use of Tantum Verde spray for adults

The aerosol bottle is equipped with a metering sprayer with a folding spray tube.

Apply the spray according to the following instructions:

Place the spray wand in a horizontal position.
If the bottle has not been used before, you should press the spray nozzle twice so that the medicine enters the spray bottle.
Insert the spray tube into your mouth.
Press the spray nozzle 4 times.
Avoid drinking or eating for 30 minutes.

The instructions for use of the Tantum Verde spray do not contain a requirement to hold your breath while spraying the drug. However, you should not take a deep breath when spraying.

One press sprays 0.17 g of medication. This volume contains 0.255 mg of benzydamine. The 30 ml bottle holds 176 sprays.

The aerosol is used every 2-3 hours. The standard duration of treatment for acute respiratory infections is 5-7 days. One bottle will last approximately this number of days.

Tantum Verde for children

In accordance with the instructions for use, Tantum Verde spray is indicated for children. It should be borne in mind that the product can be sprayed directly onto the mucous membrane of the throat for a child starting from the age of 3.

Aerosol dosage for children over 3 years of age:

up to 6 years - 3 sprays at a time;
up to 12 years - 4 sprays at a time.

After use, the drug should be monitored to ensure that the child does not consume liquid or food for at least 30 minutes.

The frequency of spraying Tantum Verde for children is every 2-3 hours.

Is it possible for children under 1 year old

There are no drugs that are specifically targeted at young children. In most cases, manufacturers in the instructions for medications limit the age of use to 3 years at best. However, young children get sick even more often, and they also need to be treated with something.

On the other hand, the big question is how much anti-inflammatory spray is required to treat infants. Infection in the baby's respiratory tract spreads quickly: pharyngitis in the morning can turn into bronchitis in the evening. For bronchitis, it makes no sense to use Tantum Verde: antibiotics are required.

In addition, when talking about use in children, it should be borne in mind that the drug:

contains alcohol;
absorbed from the mucosa and metabolized in the body.

However, pediatricians, as practice shows, prescribe Tantum Verde to infants.

Application for children 1, 2, 3 years old

The above is also true for children 1-3 years old. Despite this, many mothers believe that Tantum Verde is safer than other throat antiseptics. In addition, the anti-inflammatory effect that benzydamine has makes the child feel better, which allows the drug to be characterized as effective.

You should be guided by the age-specific dosages specified in the instructions for use of the Tantum Verde spray:

up to 2 years - 1 spray;
up to 3 years - 2 sprays.

As a general rule, the aerosol should not be sprayed directly onto the child’s throat. Spraying is done on the tongue or on the inner surface of the cheek (“behind the cheek”).

Is it possible to use Tantum Verde during pregnancy 1st, 2nd, 3rd trimester?

Despite the fact that benzydamine is absorbed from the mucous membrane and undergoes further metabolism in the body, the instructions emphasize that the spray does not have a systemic effect on the body.

The drug is safe to use in any trimester of pregnancy.

When breastfeeding

Tantum Verde is allowed to be used during lactation. Benzydamine and its breakdown products are not infiltrated into breast milk.

What does Tantum Verde spray help with?

It is advisable to use Tantum Verde for the following inflammations:

tonsils;
pharyngeal mucosa;
laryngeal mucosa;
oral mucosa (including fungal infectious diseases);
salivary glands;
periodontal tissue.

In addition, the drug is indicated in the following cases:

In cases of severe infection, the spray is used as part of antibacterial and immunomodulatory therapy.

Use for sore throat

Tantum Verde for sore throat

Inflammation of the tonsils is indicated in the instructions for use of Tantum Verde spray as the main indication. Benzidamine penetrates into inflamed tissues, accordingly, disrupting metabolic processes in microbial cells not only on the mucous membrane, but also inside the tonsils.

Consumers give good reviews about Tantum Verde spray at. But they note that it should be used in combination with antibiotics.

For laryngitis

The anti-inflammatory effect of benzydamine is effective against bacterial infections that affect the laryngeal mucosa. Penetrating into tissues, the active substance stabilizes cell membranes, stimulates healing processes, and relieves swelling of the larynx. Alcohol, which is a component of the medicine, provides an additional antibacterial effect.

As in the case of sore throat, the drug should be used as an auxiliary drug to complement antibiotic and/or antiviral therapy.

At

In the instructions for use of the Tantum Verde spray, as well as in reviews of the drug, it is noted that the product is best suited for the treatment of infectious inflammation of the pharyngeal mucosa. Benzidamine is effective against various microorganisms, including Candida fungi. The analgesic effect of the drug will help you cope with sore throat and discomfort.

Glycerol, which is a component of the spray, forms a protective lash on the mucous membrane that prevents contact with microbes.

At the same time, the drug, due to its anti-inflammatory effect, can mask a viral infection. For this reason, it is advisable to start treatment with an antiviral drug and supplement its effect with benzydamine.

Tantum Verde for stomatitis and other oral diseases

For infectious inflammation in the oral cavity, it is recommended to use Tantum Verde solution (rinse your mouth). The aerosol is used in cases where rinsing is physically impossible, for example:

for jaw injuries;
after oral surgery;
small children;
in other cases.

Inflammation of the oral mucosa - stomatitis - can be easily treated with a spray. Benzidamine relieves swelling of inflamed areas, disinfects wounds, and promotes faster healing. The same applies to inflammatory diseases affecting:

gums;
language;
salivary glands;
periodontal tissue.

Antiseptic aerosol helps with inflammation of the oral cavity caused by bacteria, as well as Candida fungus (candidiasis).

The duration of use of the drug in these cases is 10-20 days.

Operations and injuries

In accordance with the instructions for use, Tantum Verde spray can be used as an aseptic, analgesic and anti-inflammatory agent after surgical procedures, for example:

Under certain conditions (smoking, poor hygiene), microtrauma to the mucous membrane can lead to the development of infectious inflammation in the mouth. To prevent the development of an infectious process, it is recommended to use Tantum Verde.

The duration of postoperative or post-traumatic use is up to 7 days.

Other types of Tantum Verde

Italian pharmaceutical company A.C.R.A.F. produces solution, tablets and spray Forte under the trade name Tantum Verde.

Spray Forte is similar in composition to regular Tantum Verde, but has a higher concentration of benzydamine. One spray contains 0.51 mg of the substance instead of 0.255 mg in the usual one. For this reason, the instructions for Tantum Verde Forte spray specify that the drug is contraindicated in patients under 18 years of age.

The increased concentration of the active substance allows you to use the drug less often (2-6 times a day) with fewer sprays (2-4 at a time).

Forte is available in 15 ml bottles. It is enough for 88 sprays.

for whom regular Tantum does not help effectively;
with severe inflammation;
for those who want to spray the drug less often.

Tantum Verde rinse solution

According to the instructions, the Tantum Verde rinse solution is suitable for:

for the treatment of infectious inflammation;
for use for preventive and hygienic purposes.

Rinse with 15 ml of solution, which is measured using a special measuring cup (included). In case of an active inflammatory process, rinse the mouth with undiluted solution three times a day.

Contraindications for Tantum Verde solution include use of the product by children under 12 years of age: due to the large amount of benzydamine in one dose (22.5 mg).

Tantum Verde tablets

Tantum Verde lozenges are a suitable remedy for the complex treatment of sore throats and infectious lesions of the oral mucosa. One tablet contains 3 mg of benzydamine. Dosage regimen: long-term resorption, 1 tablet three times a day.

Tantum Verde throat lozenges are contraindicated for children, who, not realizing the meaning of the process, may swallow the medicine.

What is better Tantum Verde spray or Tablets

The choice of tablets or spray is largely a matter of individual preference.

Several considerations can be made in favor of the tablet form of the drug:

The tablets are suitable for those for whom it is difficult to spray an aerosol into the throat every 2-3 hours.
The tablets do not contain alcohol, which is good, for example, for children.

At the same time, inflammation of the throat mucosa is more effectively treated with a spray. More frequent application of the drug more successfully copes with the infection, eliminates swelling and discomfort. In addition, treatment with an aerosol will be slightly cheaper than with tablets.

Analogs of Tantum Verde spray are cheaper

Exact analogs of Tantum Verde throat spray:

Oralcept (Macedonia);
Tenflex (Türkiye).

Both drugs are cheaper than the Italian drug. Oralcept - insignificant. Tenflex - by 20%.

Analogues for children

Cheaper analogues of Tantum Verde for children are Oralcept and Tenflex. These drugs are identical in their composition and concentration of benzydamine.

Comparison with other throat medications

What is better Hexoral or Tantum Verde

has no taste or smell;
does not contain alcohol;
fights bacteria, viruses and fungi;
indicated for all categories of patients without restrictions;
budgetary means.

The drug does not relieve inflammation or relieve pain.

Tantum Verde or Ingalipt

A domestically produced antibacterial product based on sulfonamide. Herbal components fight inflammation and relieve pain slightly.

The advantage of Ingalipt is its reasonable cost.

Streptocide is an effective antimicrobial agent. But due to long-term use, some strains of bacteria have become resistant to it.

Probably, Tantum Verde in this pair can be called the best drug.

Lizobakt or Tantum Verde

Antiseptic Lizobact is presented in the form of lozenges.

Lysobakt is based not on a synthetic substance, but on an enzyme of animal origin, isolated from biological material: milk, chicken eggs, biological fluids of animals (for example, saliva, which explains its disinfecting property). For many patients, this is an undeniable advantage of the drug.

Lizobakt also has disadvantages:

Like any protein enzyme, lysocine can cause allergies.
The lactose contained in the drug makes its use impossible for people with lactose intolerance.
The dosage for adults is 6-8 tablets per day - making the use of the drug relatively expensive.

In all likelihood, Tantum Verde will be a more profitable and effective medicine compared to Lizobact.

Good day, dear friends! The season of constant colds is in full swing and it is important to have reliable and convenient medicine on hand.

Let's find out more information about one such medicine today - Tantum Verde spray. It belongs to modern drugs with effects against microbes and inflammation.

The medicine is especially effective for the treatment of all kinds of inflammatory processes in the respiratory tract, throat and mucous membranes of the mouth. It has a positive effect on sore throat, stomatitis or laryngitis.

The spray relieves negative symptoms and eliminates soreness and other discomfort in the throat. So, let's find out at what age it can be used and how to do it correctly.

Tantum Verde is produced by pharmaceutical companies from Italy. You can purchase the product in pharmacies and even without a prescription from a doctor. It is packaged in bottles with a capacity of 15 and 30 ml.
The drug is convenient to use, thanks to a special spout that folds easily. This feature allows you to carry the product with you.

The drug is suitable for children, but it cannot be used for babies under one year old or even 2 years old.

When using the drug, it is worth considering that it is absorbed from mucous surfaces. It happens that pediatricians prescribe this remedy even to infants.
It is not recommended to spray the aerosol on the mucous membrane of the throat. Spraying is performed on the surface of the cheeks and on the tongue.
The drug does not affect the body and internal organs, so it is prescribed to pregnant women.

Composition of tantum verde spray

Let's look at the composition of the drug. The main component is benzydamine. This substance inhibits the activity of pathogenic microorganisms. It penetrates well into the membranes of bacterial cells and at the same time causes the death of infectious agents.

There are also auxiliary components - glycerol, menthol flavor, saccharin, polysorbate and ethanol. Menthol flavoring adds a pleasant mint taste.

How the drug works

The drug belongs to the group of indazoles. This is a non-steroidal drug with high anti-inflammatory activity. It has an analgesic and anti-inflammatory effect, as well as an antiseptic effect.

The mechanism of action of the drug is associated with inhibition of prostaglandin production. The composition prevents the reproduction of metabolic cellular structures.
The medicine is well absorbed through mucous surfaces and passes into inflamed tissues. However, it can be found in small quantities in the blood plasma. Benzydamine is excreted by the kidneys.

Indications for use

The drug is used for inflammatory diseases of the mouth and throat.

It is worth knowing about the main indications:

Laryngitis, tonsillitis and pharyngitis.
and gingivitis.
Candidiasis of the mucous membrane.
Used after tooth extraction and treatment.
Periodontal disease.

Used in complex therapy for inflammatory and infectious diseases. The drug is especially effective for angina.

Benzidamine penetrates diseased tissues and destroys metabolic processes in microbial cells. For such a disease, Tantum Verde is recommended to be used together with antibiotics.

The effect of the active substance is effective against bacterial infections that affect the laryngeal mucosa. Upon penetration into the tissue, the component stimulates healing processes and eliminates swelling.
The medicine is also used for pharyngitis. Benzidamine copes well with various microorganisms, for example, fungi. The analgesic effect will help you cope with sore and sore throat.

The drug contains Glycerol, which creates a protective film on the mucous membrane, which prevents the penetration of microbes.
For infectious diseases in the oral cavity, use Tantum Verde solution for rinsing. Rinse with 15 ml of solution.

They are measured in special containers that are included in the package. If the inflammation is severe, then use an undiluted solution three times a day.

The aerosol is effective when rinsing is not possible:

after surgery on the oral cavity;
for jaw injuries;
for small children.

It is good to treat stomatitis with a spray. The active component disinfects wounds, reduces swelling and promotes rapid healing.

For inflammation caused by Candida fungi, the course of treatment lasts approximately 10-20 days. In some cases, lollipops are used.

They treat infections and inflammation of the throat. The tablet contains 3 mg of benzydamine. You need to dissolve one tablet three times a day.

Lollipops should not be given to small children.

Benefits of the medicine

Tantum Verde is often prescribed for children due to the following benefits:

Minimal side effects after treatment.
Effect on fungi and bacteria.
Large list of indications.
Excellent absorption with good penetration into inflamed tissues.
The result is noticeable after short use.
Simple and convenient use.
Drug safety.

The medicine can be used even during pregnancy or lactation. In this case, the instructions for use must be strictly followed.

Contraindications and side effects

There are also certain contraindications:

age up to 3 years;
sensitivity to benzydamine.

Caution should be exercised in case of bronchial asthma, as well as in case of hypersensitivity to acetylsalicylic acid.
The following side effects may occur after use:

local reactions are manifested by dry mouth, burning in the oral cavity and slight numbness;
allergic reactions occur with hypersensitivity. This may include skin itching, swelling and anaphylactic reactions.

Features of application

The drug is used topically and only after meals. One injection contains 0.255 mg of benzydamine.

The dosage depends on the patient's age:

For children from 3 to 6 years old, 1 injection is required for every 4 kg of weight. A single dose should not exceed 4 injections. Manipulations can be carried out 2-6 times a day.
Children from 6 to 12 years old: 4 injections.
Adults and children over 12 years old – 4-8 injections.

You should not use the drug for more than a week. If after this there is no improvement, then consultation with a doctor is required.

Here are the basic instructions:

Turn the white tube or cannula into a vertical position relative to the bottle.
Insert it into your mouth and direct it to the inflamed areas.
Press the dispenser as many times as recommended in the instructions.
Hold your breath while injecting.

What analogues are there?

Now let’s figure out how much the drug costs and what analogues exist. The price of Tantum Verde Forte varies within 250-275 rubles.

Pharmacies also have drugs with identical effects and different prices. If you need a cheaper analogue, then you can choose Grammidin Neo or Lugol.

The following medications have the same price: Ingalipt, Hexoral and Orasept. To choose the right option, you should study different reviews.

Let's take a closer look at the analogues:

Inhalipt is based on essential oils and streptocide. It is effective for throat diseases.
Hexoral also helps with many inflammatory diseases of the ENT organs, but its active ingredient is hexetidine.
Cametone is a complex product containing anti-inflammatory and analgesic components.
Proposol is a plant-based drug.

Remember that when using any medicine, even the gentlest one, it is important to follow the correct dosage.

See you soon, friends!

Composition on 100 ml rinse solution

Active ingredient: benzydamine hydrochloride - 0.15 g (which corresponds to 0.18 g in one 120 ml bottle);

auxiliaryComponents: ethanol 96%, glycerin (glycerol), methyl parahydroxybenzoate, menthol flavor, saccharin, sodium bicarbonate, polysorbate 20, quinoline yellow dye 70% (E l04), patent blue dye 85% (E 131), purified water.

Description

Rinse solution 0.15%: transparent green liquid with a characteristic mint odor.

Pharmacological group

Other products for topical use for diseases of the oral cavity.

CodeATX: A01AD02

Pharmacological properties

Pharmacodynamics

Benzydamine is a non-steroidal anti-inflammatory drug. Has anti-inflammatory and local analgesic effect.

The mechanism of action of the drug is associated with its suppressive activity of pro-inflammatory cytokines, since it inhibits the synthesis of TNFα and, to a lesser extent, IL-lβ and MCP-1, and inhibition of prostaglandin synthesis.

Clinical studies have shown that benzydamine is effective in the treatment of localized inflammatory processes in the mouth and throat.

Pharmacokinetics

When applied topically, the drug is well absorbed through the mucous membranes and penetrates into inflamed tissues, reaching effective concentrations due to its ability to penetrate the superficial epithelial layer.

Excretion of the drug occurs mainly by the kidneys and through the intestines in the form of metabolites or conjugation products.

Dosage forms for topical use do not have a systemic effect.

Indications for use

Symptomatic treatment of irritations and inflammatory conditions, including those associated with pain in the mouth and throat (eg, pharyngitis, gingivitis, stomatitis), as well as after conservative treatment or tooth extraction.

Contraindications

Hypersensitivity to any of the components of the drug;

Pregnancy and breastfeeding

There are no adequate data available on the use of benzydamine during pregnancy and breastfeeding. The ability of this drug to pass into breast milk has not been studied. Data from animal studies of the drug are insufficient to draw any conclusions about the effect of this drug during pregnancy and breastfeeding. The potential risk to humans cannot be assessed. Tantum Verde should not be used during pregnancy and breastfeeding.

Directions for use and doses

For adults, elderly patients and children over 12 years of age, use a solution for gargling or mouthwash, 15 ml (measured using a measuring cup) 2-3 times a day.

Do not use the drug in children under 12 years of age due to the possibility of swallowing the solution while rinsing the mouth. It is recommended to use the drug in the form of an undiluted solution or a diluted solution (mix 15 ml of the drug and 15 ml of water in a measuring cup).

Duration of treatment:

For inflammatory diseases of the mouth and throat (of various etiologies): 3-5 days;

For dental pathology: 3-5 days;

When using the drug for a long time, consult a doctor.

Side effects

The table below shows side effects classified by organ or organ system according to MedDRA. The frequency categories of side effects are defined as follows: very common (≥ 1/10); frequent (from ≥ 1/100 to

Overdose

Very rarely, overdose symptoms such as excitability, convulsions, sweating, ataxia, tremor and vomiting have been reported in children after oral administration of benzydamine in doses that are approximately 300 times higher than recommended.

In case of acute overdose, only symptomatic treatment is possible; The stomach should be cleared by inducing vomiting or gastric lavage, and the patient should be under medical supervision with supportive care and adequate hydration.

Interaction with other drugs

No clinically significant interaction of Tantum® Verde with other drugs has been established.

special instructions

The use of this drug, especially with long-term therapy, may cause a sensitivity reaction. In this case, treatment should be interrupted and a doctor should be consulted to determine acceptable therapy.

In a limited number of patients, the oropharyngeal form of an ulcer may be a sign of more serious pathologies. If symptoms persist beyond 3 days, the patient should consult their doctor or dentist, as appropriate.

The drug should be prescribed with caution to patients with a history of bronchial asthma, since bronchospasms may occur in patients in this group.

Tantum® Verde contains methyl parahydroxybenzoate, which can cause allergic reactions (including delayed ones).

For patients involved in sports: the use of drugs containing ethyl alcohol may test positive for doping according to the blood alcohol limits set by some sports federations.

Effect on ability to lead road transport sports and machine control

The drug does not affect the ability to drive vehicles or other activities requiring increased attention.

Release form

120 ml of solution in a colorless transparent glass bottle, closed with a screw cap made of high density polyethylene or polypropylene with a polyethylene sealing ring; The bottle is accompanied by a polypropylene cup with graduations of 15 and 30 ml. The bottle, along with a graduated glass and instructions for use, is placed in a cardboard box.

Best before date

Do not use after expiration date.

Storage conditions

Store at a temperature not exceeding 25°C in a place protected from light. Keep out of the reach of children.

Conditions of leave from pharmacies

Over the counter.

Information about the manufacturer (applicant)

”Aziende Quimique Riunite Angelini Francesco A.C.R.A.F. S.p.A.

Aziende Chimiche Riunite Angelini Francesco - A.C.R.A.F. S.p.A.

Viale Amelia, 70, Rome, Italy / Viale Amelia, 70, Rome, Italy

Organization representing the interests of the manufacturer

JSC "MRA", st. Zhirnyu 26, LT-02120 Vilnius, Lithuania, tel. +370 5 2649010

UAB "MRA", Zirniu str. 26, LT-02120 Vilnius, Lithuania, Phone: +370 5 2649010

Tantum verde (active ingredient benzydamine) is a non-steroidal anti-inflammatory drug that is a derivative of indazole in its chemical structure. It has an anti-inflammatory and local analgesic effect, and has an antiseptic effect against a number of pathogenic and conditionally pathogenic microorganisms. The area of application of tantum verde is infectious and inflammatory diseases of the ENT organs (ear, throat, nose, larynx) and the oral cavity of various etiologies.

The antibacterial effect of the drug is based on its ability to quickly penetrate the membranes of microorganisms and damage cellular structures, disrupt metabolic processes until cell death. Tantum verde has an antifungal effect against Candida albicans. The drug causes structural changes in the cell wall of the fungus and destructively interferes with the metabolic chains of mycetes, preventing their reproduction. Unlike other non-steroidal anti-inflammatory drugs, which act mainly on the synthesis of prostaglandins, tantum verde realizes its pharmacological effects by suppressing the synthesis of cytokines. Thanks to this, the drug has a pronounced anti-inflammatory effect without clinically significant side effects. The analgesic effect of tantum verde is also associated with a membrane-stabilizing effect. Due to its high lipophilicity (affinity for fats), when applied topically, the drug has an antimicrobial effect against both gram-positive and gram-negative aerobes and anaerobes. In the course of numerous clinical trials, it has been demonstrated that during treatment with the drug Tantum Verde, the feeling of pain and discomfort in the oral cavity is significantly dulled already on the first day of the pharmacotherapeutic course. It should be noted that the use of non-steroidal anti-inflammatory drugs in the combined treatment of oral diseases is now a generally accepted practice.

One of the characteristic properties of tantum verde is its ability to be well absorbed through mucous membranes, which facilitates the penetration of the pharmacologically active substance into the site of inflammation and has a local analgesic effect. Tantum verde is reported to have approximately half the local analgesic potential of the local anesthetic tetracaine. The duration of pain relief in the oral cavity when applied topically is about one and a half hours. The analgesic effect of the drug increases as inflammatory processes are suppressed and swelling is reduced. Already on the second day of using Tantum Verde, there is a decrease in pain (including when swallowing), burning, and otalgia, which makes it possible to eat normally.

Tantum verde is available in three dosage forms: topical solution, dosed topical spray and lozenges. To rinse the mouth or throat, use 15 ml of solution, measured using a cup inserted into the package, 2-3 times a day. For rinsing, you can use either diluted (15 ml of the drug + 15 ml of water are mixed in a measuring cup) or undiluted. In the first case, the purpose of use is to suppress the inflammatory process, in the second - to maintain the rules of oral and throat hygiene. The spray is prescribed in 4–8 doses (adults), 4 doses (children aged 6–12 years). For children 3-6 years old, the dose is determined depending on body weight: 1 dose for every 4 kg. The spray must be used with caution to avoid contact with the eyes. The frequency of taking the drug is the same for all age groups: every 1.5–3 hours. Lozenges should be taken 1 3-4 times a day. The tablet should be kept in the mouth until completely absorbed (the longer this happens, the stronger the therapeutic effect will be).

Pharmacology

Benzidamine is a non-steroidal anti-inflammatory drug that belongs to the indazoles group. It has an anti-inflammatory and local analgesic effect, and has an antiseptic effect against a wide range of microorganisms.

The mechanism of action of the drug is associated with the stabilization of cell membranes and inhibition of prostaglandin synthesis.

Benzidamine has an antibacterial and specific antimicrobial effect due to rapid penetration through the membranes of microorganisms with subsequent damage to cellular structures, disruption of metabolic processes and cell lysis.

Has antifungal effect against Candida albicans. Causes structural modifications of the cell wall of fungi and the metabolic chains of mycetes, thus preventing their reproduction, which was the basis for the use of benzydamine for inflammatory processes in the oral cavity, including infectious etiology.

Pharmacokinetics

When applied topically, the drug is well absorbed through the mucous membranes and penetrates into inflamed tissues.

Excretion of the drug occurs mainly by the kidneys and through the intestines in the form of metabolites or conjugation products.

Dosage forms for topical use do not have a systemic effect and do not pass into breast milk.

Release form

Lozenges are green, translucent, square, with a depression in the center, with a characteristic mint-lemon odor.

Excipients: isomaltose, racementhol, aspartame, citric acid monohydrate, mint flavor, lemon flavor, quinoline yellow dye (E104), indigo carmine dye (E132).

1 PC. - wax paper wrappers (10) - double-layer aluminum foil wrappers (2) - cardboard packs.

Dosage

Lozenges 3 mg: adults, elderly patients and children over 3 years old, take 1 tablet 3-4 times a day. Keep the tablet in your mouth until completely dissolved (for greater effect, preferably for as long as possible).

Solution for topical use 0.15%: adults, elderly patients and children over 12 years of age are prescribed for gargling or mouthwash, use 15 ml of the drug (measuring cup included) 2-3 times a day.

An undiluted solution is used for rinsing during inflammatory processes;

Use the diluted solution (15 ml of the drug and 15 ml of water in a measuring cup) daily for hygienic rinsing of the mouth and throat.

Spray for topical use dosed 0.255 mg/dose: adults and elderly patients are prescribed 4-8 doses every 1.5-3 hours;

Children aged 3-6 years - 1-4 doses (maximum 4 doses) every 1.5-3 hours;

Children aged 6-12 years: 4 doses every 1.5-3 hours.

A course of treatment:

For inflammatory diseases of the oral cavity and ENT organs (of various etiologies): from 4 to 15 days;

For odonto-dental pathology: from 6 to 25 days;

After surgical interventions and injuries (tonsillectomy, jaw fractures) when using a spray and solution: from 4 to 7 days.

When using the drug for long periods, consult a doctor.

Overdose

Currently, no cases of overdose of Tantum ® Verde have been reported.

Interaction

No clinically significant interaction of the drug Tantum ® Verde with other drugs has been established.

Side effects

Local reactions: dry mouth, numbness, burning sensation in the mouth.

Allergic reactions: skin rash.

Very rare: laryngospasm.

Indications

Inflammatory diseases of the oral cavity and ENT organs (of various etiologies):

gingivitis, glossitis, stomatitis (including after radiation and chemotherapy);
sore throat, pharyngitis, laryngitis, tonsillitis;
candidiasis of the oral mucosa (as part of combination therapy);
calculous inflammation of the salivary glands;
after surgical interventions and injuries (tonsillectomy, jaw fractures);
after treatment or tooth extraction;
periodontal disease.

For infectious and inflammatory diseases requiring systemic treatment, it is necessary to use Tantum ® Verde as part of combination therapy.

Contraindications

hypersensitivity to any of the components of the drug;
children under 3 years of age;
children under 12 years of age (for using a solution of 0.15%);
phenylketonuria (for use of tablets).

Features of application

Use during pregnancy and breastfeeding

It is possible to use the drug during pregnancy and lactation (breastfeeding).

Use in children

Contraindicated for children under 3 years of age. The 0.15% solution is contraindicated in children under 12 years of age.

special instructions

If a burning sensation occurs when using the solution, the solution should first be diluted with water twice by bringing the water level to the mark in a graduated glass.

Avoid getting the spray in your eyes.

Impact on the ability to drive vehicles and operate machinery

The drug does not affect the ability to drive vehicles or other activities requiring increased attention.

Tantum verde is a non-steroidal anti-inflammatory drug that is suitable for topical use. The medicine is actively used in otolaryngology and dentistry. To achieve good results, it is very important to strictly follow the instructions.

Composition, release form, packaging

Tantum verde has several forms of release:

Tablet form - intended for resorption. 1 tablet contains 3 mg of benzydamine. The blister contains 10 pieces. The package contains 2 blisters.
The solution has a green tint and a transparent consistency. 1 ml contains 1.5 mg of benzydamine. The drug is in a glass bottle with a capacity of 120 ml.
Spray - packaged in 30 ml bags and is a solution. Each dose contains 255 mcg of benzydamine.

Manufacturer

The drug is produced by the Italian company Aziende Chimiche Riunite Angelini Francesco.

Indications

The medicine is prescribed for inflammation in the mouth and damage to the ENT organs. The main indications include:

pharyngitis;
glossitis;
stomatitis;
periodontal disease;
laryngitis;
inflammatory damage to the salivary glands, which is calculous in nature;
surgical interventions and traumatic injuries;
gingivitis;
treatment or removal of teeth.

If an infectious or inflammatory pathology requires systemic therapy, tantum verde is used as part of a comprehensive treatment.

Contraindications

The product must not be used in the following situations:

high sensitivity to the components of the drug;
age less than 3 years;
phenylketonuria – for tablet form;
age less than 12 years - for a solution with a concentration of 0.15%.

Mechanism of action

Benzydamine belongs to the category of non-steroidal anti-inflammatory substances, which are included in the group of indazoles. The medicine produces a local analgesic effect and successfully copes with inflammation. In addition, the substance has an antiseptic effect and helps against infection by a variety of microorganisms.

The principle of action of the drug is based on the stabilization of cell membranes. The drug leads to inhibition of prostaglandin production.

Benzidamine produces an antibacterial effect and helps achieve a special antimicrobial effect. This is achieved due to the rapid penetration of microorganisms through cell membranes, damaging structures and changing metabolism. In addition, the medicine helps cope with Candida Albicans fungi.

Instructions for use

The tablet form is prescribed to adults and children over 3 years of age. Usually 1 tablet is prescribed. They must be used up to 4 times a day. The medicine should be left in the mouth until it is completely dissolved.

The solution is prescribed to adults and children over 12 years of age. It is indicated for rinsing. Usually you need to apply 15 ml of medication up to 3 times a day.

In its pure form, the product is used for inflammation. A substance that is mixed in equal parts with water is used for hygiene purposes.

Spray for local use can be used as follows:

adult patients - 4-8 doses with an interval of 1.5-3 hours;
at 3-6 years – 1-4 doses with an interval of 1.5-3 hours;
at 6-12 years old - 4 doses with a break of 1.5-3 hours.

The duration of treatment depends on the diagnosis:

If the otolaryngological organs and mouth are affected, therapy lasts from 4 to 15 days.
After operations and traumatic injuries, a solution or spray is prescribed. Treatment usually lasts 4-7 days.
For dental problems, the drug is used for 6 to 25 days.

If you need to extend therapy, you must consult your doctor.

Side effects

In some situations, the drug provokes undesirable reactions:

feeling of dry mouth;
loss of sensitivity and burning sensation in the mouth;
increased drowsiness.

Overdose

When used locally, overdose is impossible. When a large amount of the drug enters the body, there is a risk of signs of intoxication. They appear as follows.